Global Assault now also features a destructible environment, allowing you to seize control of the environment and create ultimate destruction. It features many new weapons, new vehicles, and new powers that were not available in the original.

Global Assault is the sequel to the original BattleTanx. Cassandra leads Griffin and Madison all across America and Europe in a frantic search for Brandon, who may have psychic abilities that can save the world. However, the evil QueenLord, Cassandra, captures him. In the midst of the chaos, Griffin and Madison escape back to San Francisco with their new baby boy Brandon, where they hope to rebuild a better society. Mobs and warlords have emerged trying to claim the world's last surviving women. There is no form of government, form of justice, and the only way to survive is lookout for yourself. Instinct has taken over, and the only rule is mob rule. A nuclear holocaust has caused 99.9% of the women in the entire world to die out, leaving mankind desperate to search for women for reproduction.

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